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Annual Arthur Benton Lectures

    • 16 Mar 2026
    • 7:00 PM - 8:00 PM
    • Manhattan Eye, Ear & Throat Hospital; 210 E. 64th Street; New York, New York 10065 / Also virtual option
    Register

    The 41st Annual Arthur L. Benton Lecture

     

    John DeLuca, PhD, ABPP

    Fatigue: What is it, Can we measure it, and Can we treat it?

    IN-PERSON AND VIRTUAL EVENT

    IN-PERSON ATTENDANCE: WILL BE CAPPED AT 70

    (bring ID to enter)

    LOCATION:

    Manhattan Eye, Ear & Throat Hospital

    210 E. 64th Street

    New York, New York 10065

    *Members: Free attendance & Free 1.0 CE credit

    *Non-members: $30, which includes 1.0 CE credit 


    Abstract: Fatigue is a multi-faceted symptom, which is both pervasive and persistent. It affects ~20% of the general population and is a particular problem following neurological disease or infection. For instance, as many as 90% of individuals with multiple sclerosis report fatigue to be their worst symptom. Similarly, following viral infection such as COVID-19, ~40% of patients report elevated levels of fatigue. However, despite its prevalence, fatigue remains poorly understood. This is due, in large part, to an historical reliance on self-report measures to assess fatigue. This talk will trace the history of fatigue, explore ideas about how it is defined, assessed and treated. This presentation will discuss how fatigue is beginning to be understood through the use of rigorous experimental design and novel objective metrics such as signal detection theory and neuroimaging. New research-based approaches for treatment of fatigue will be discussed.

    John DeLuca, PhD, is the Senior Vice President for Research and Training at Kessler Foundation, a Professor in the Department of Physical Medicine & Rehabilitation, and the Department of Neurology at Rutgers, New Jersey Medical School. He is board certified in Rehabilitation Psychology by the American Board of Professional Psychology. Dr. DeLuca has been involved in neuropsychology and rehabilitation research for over 30 years. He is internationally known for his research on disorders of memory and information processing in a variety of clinical populations including: multiple sclerosis, traumatic brain injury, aneurysmal subarachnoid hemorrhage, and chronic fatigue syndrome. Dr. DeLuca has published over 425 articles, books and book chapters in these areas, has edited 7 books in neuropsychology, neuroimaging and rehabilitation, and is a co-Chief editor for the “Encyclopedia of Clinical Neuropsychology.” He has received over 65 million dollars in grant support for his research.  Dr. DeLuca's most recent research ventures include the cerebral mapping of human cognitive processes using functional neuroimaging, as well as the development of research-based techniques to improve cognitive impairment. He serves on the editorial boards of many journals and has received numerous national and international awards in recognition of his work.

    Learning Objectives:

    1. Understand the challenges with measuring and assessing fatigue.

    2. Have a better understanding of the impact on fatigue and performance.

    3. Have a better understanding of the relationship between fatigue and the brain.

    Financial Disclosures: Dr. DeLuca serves(ed) on an Advisory board for: Biogen, Novartis, Celgene/BMS, Roche, Janssen, MedRhythms. He Serves(ed) as a Consultant for: Celgene/BMS, Sanofi – Genzyme. He serves(ed) on a Speakers Bureau for: Biogen, EMD Serono, Sanofi – Genzyme. He has received funding from: Biogen, EMD Serono, Roche, BMS, NMSS, CMSC, NIH, MS Society of Canada.

    References:

    • 1.      Wylie GR, Román CAF, Buckey JC Jr, Chiaravalloti ND, Falvo MJ, Ford JC, Genova HM, Niemczak CE, Roth RM, DeLuca J. The differential effect of chronological age and brain age on cognitive fatigue: new metrics, new insights. J Neurol. 2026 Jan 7;273(1):63. doi: 10.1007/s00415-025-13584-1. PMID: 41498952; PMCID: PMC12779680.
    • 2.      Román CAF, DeLuca J, Yao B, Genova HM, Wylie GR. Signal Detection Theory as a Novel Tool to Understand Cognitive Fatigue in Individuals With Multiple Sclerosis. Front Behav Neurosci. 2022 Mar 16;16:828566. doi: 10.3389/fnbeh.2022.828566. PMID: 35368296; PMCID: PMC8966482.
    • 3.      Wylie GR, Yao B, Sandry J, DeLuca J. Using Signal Detection Theory to Better Understand Cognitive Fatigue. Front Psychol. 2021 Jan 15;11:579188. doi: 10.3389/fpsyg.2020.579188. PMID: 33519595; PMCID: PMC7844088.
    • 4.      Dobryakova E, Genova H, Schneider V, Chiaravalloti ND, Spirou A, Wylie GR, DeLuca J. Reward presentation reduces on-task fatigue in traumatic brain injury. Cortex. 2020 May;126:16-25. doi: 10.1016/j.cortex.2020.01.003. Epub 2020 Jan 24. PMID: 32062140.
    • 5.      Dobryakova E, Hulst HE, Spirou A, Chiaravalloti ND, Genova HM, Wylie GR, DeLuca J. Fronto-striatal network activation leads to less fatigue in multiple sclerosis. Mult Scler. 2018 Aug;24(9):1174-1182. doi: 10.1177/1352458517717087. Epub 2017 Jun 19. PMID: 28627957.

    *New York Neuropsychology Group is recognized by the New York State Education Department's State Board for Psychology as an approved provider of continuing education for licensed psychologists #PSY-0107 

    *New York Neuropsychology Group is approved by the American Psychological Association to sponsor continuing education for psychologists. NYNG maintains responsibility for this program and its content. 

    Refund Policy: Full refund will be provided if cancellation occurs up to 24 hours prior to the event. Cancellation requests made within 24 hours are non-refundable.  

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22 Jan 2024 39th Annual Arthur Benton Lecture / “Cognitive and Biomarker Changes During Preclinical Alzheimer’s Disease” / Marilyn Albert, PhD
9 Jan 2023 38th Annual Arthur Benton Lecture / "Translating Neurobiological Insights concerning Prefrontal Cortex and Executive Functions into Clinical Implications" / Adele Diamond, PhD, FRSC
28 Feb 2022 37th Annual Arthur Benton Lecture / "The Biology of Feeling and the Nature of Consciousness" / Antonio Damasio, MD, PhD
26 Jan 2021 36th Annual Arthur Benton Lecture / "Improving the Human Brain" / Michael Posner, PhD
27 Jan 2020 35th Annual Arthur Benton Lecture / "Reducing Diagnostic Uncertainty: The Role of Evidence-Based Practices in Clinical Practice and Research" / Gordon Chelune, PhD
23 Jan 2019 34th Annual Arthur Benton Lecture / "Constraint-Induced Movement Therapy: From Monkey Lab To Human Rehabilitation" / Edward Taub, PhD
8 Jan 2018 33rd Annual Arthur Benton Lecture / "Investigations of Preclinical Stage of Alzheimer’s Disease" / Stephen Rao, PhD
9 Jan 2017 32nd Annual Arthur Benton Lecture / "Creativity & The Brain" / Kenneth Heilman, MD
11 Jan 2016 31st Annual Arthur Benton Lecture / "My Path to Neuropsychology and Cognitive Reserve" / Yaakov Stern, PhD
12 Jan 2015 30th Annual Arthur Benton Lecture / "A Novel Approach to Hemispheric Specialization in Novelty Processing (Pun Intended)" / Elkhonon Goldberg, PhD
27 Nov 2014 29th Annual Arthur Benton Lecture / "Optimal Outcome in Children with a History of Autism" / Deborah Fein, PhD
4 Jan 2013 28th Annual Arthur Benton Lecture / "Anatomical Functional Organization of the Frontal Lobes: Implications for Assessment and Rehabilitation" / Donald Stuss, PhD
9 Jan 2012 27th Annual Arthur Benton Lecture / "Profiles of Dementia: Four Neuropsychological, Neuroanatomic and Neuropathologic Phenotypes" / Sandra Weintraub, PhD
10 Jan 2011 26th Annual Arthur Benton Lecture / "Fatal Attraction: The Tangled Relationship of Neuropsychology and IQ Tests" / Maureen Dennis, PhD
11 Jan 2010 25th Annual Arthur Benton Lecture / "Cognitive Changes With Aging: What is Normal & What is Not?" / Linas Bieliauskas, PhD
22 Apr 2009 24th Annual Arthur Benton Lecture / "Controversies in Pediatric Bipolar Disorder: How Neuropsychological Findings and Concepts Help to Clarify the Issues" / Steve Mattis, PhD, ABPP-CN
27 Jan 2007 22nd Annual Arthur Benton Lecture / "Pioneers of Neuropsychology: An Insider’s Guide to Arthur Benton" / Kerry Hamsher, PhD
7 Nov 2006 21st Annual Arthur Benton Lecture / "Neuropsychology of Cognitive Aging: Diagnosis & Experimental Therapeutics" / Mary Sano, PhD
29 Nov 2005 20th Annual Arthur Benton Lecture / "Memory Impairment" / Herman Buschke, MD
1 Dec 2004 19th Annual Arthur Benton Lecture / "Brain Basis of Consciousness: Evidence From Neuropsychology" / Marcel Kinsbourne, PhD
13 Nov 2003 18th Annual Arthur Benton Lecture / "The Neuropsychology of Emotions: Clinical Implications" / Joan Borod, PhD
25 Nov 2002 17th Annual Arthur Benton Lecture / "Evolutionary Neuroanatomy and Schizophrenia" / Robert Bilder, PhD, ABPP
1 Jan 2001 16th Annual Arthur Benton Lecture / "" /
28 Nov 2000 15th Annual Arthur Benton Lecture / "Cortical Memory" / Joaquin Fuster, PhD
15 Nov 1999 14th Annual Arthur Benton Lecture / "Neuropsychological Rehabilitation: a Day Program Based on Luria’s Theory" / Anne-Lise Christensen, PhD
30 Nov 1998 13th Annual Arthur Benton Lecture / "The Organization of Knowledge Systems in the Brain" / Elizabeth Warrington, PhD
11 Nov 1997 12th Annual Arthur Benton Lecture / "Biological Influences on Sex Differences in Cognition" / Doreen Kimura, PhD
25 Nov 1996 11th Annual Arthur Benton Lecture / "Processing Deficits in Amnesia" / Laird Cermak, PhD
20 Nov 1995 10th Annual Arthur Benton Lecture / "Body Sensation in the development of Self: a Neuropsychological Analysis" / Marcel Kinsbourne, PhD
21 Nov 1994 9th Annual Arthur Benton Lecture / "Degrees of Modularity and the Concept of Self in the Dual Brain" / Eran Zaidel, PhD
1 Jan 1993 8th Annual Arthur Benton Lecture / "" /
1 Jan 1992 7th Annual Arthur Benton Lecture / "" /
1 Nov 1991 6th Annual Arthur Benton Lecture / "" /
17 Dec 1990 5th Annual Arthur Benton Lecture / "The Aftereffects of Stress on The Brain" / Dennis D. Kelly, PhD
20 Nov 1989 4th Annual Arthur Benton Lecture / "Memory Systems: A Psychobiological Perspective" / Herbert Weingartner, PhD
21 Nov 1988 3rd Annual Arthur Benton Lecture / "New Prospects For Understanding The Frontal Lobes" / Brenda Milner, PhD
16 Nov 1987 2nd Annual Arthur Benton Lecture / "Parsing Memory: The Process Approach to Assessing Dysfunctional Memory" / Edith Kaplan, PhD
8 Dec 1986 1st Annual Arthur Benton Lecture / "The Evolution of Clinical Neuropsychology As Reflected in The Study Of Visual-Perceptual Disorders" / Arthur L. Benton, PhD

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