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2022 Frank L. LeFever Spring Conference - Lecture 2 / "Cognitive and Mood Symptoms Following Recovery from Covid-19. Implications for Intervention" / Faith M. Gunning, PhD

  • 2 May 2022
  • 7:00 PM - 8:00 PM
  • Zoom link to follow


Monday, May 2nd @ 7-8pm EST

The Second of Three Lectures in our 43rd Annual Frank L LeFever Spring Conference

Our 3 Part Virtual Conference will focus on Covid-19

   Faith M. Gunning, PhD  

Cognitive and mood symptoms following recovery from Covid-19.

   Implications for Intervention  

Abstract: Convergent evidence indicates that a subset of individuals will experience persistence of cognitive and mood symptoms following acute COVID-19 infection. In early work, we demonstrated that during inpatient rehabilitation these sequelae can include a range of neurocognitive deficits, including attentional disturbances. Subsequent cohort studies and survey-based studies have shown that new or worsening mood and cognitive disorders are common. Depressive episodes following COVID-19 may present with somewhat different symptoms than other depressive episodes and reflect distinct risk factors. The mechanisms by which COVID-19 contributes to such neurocognitive and neuropsychiatric symptoms are not yet understood, with secondary effects of inflammation representing a leading hypothesis. Regardless of mechanism, identifying efficacious and scalable strategies for addressing neuropsychiatric sequelae of COVID-19 is a critical next step. Examples of such approaches will be presented.  


Dr. Gunning combines her background as a clinical neuropsychologist with her expertise in cognitive neuroscience to conduct a program of research funded by the National Institutes of Health to use performance-based behavioral and cognitive measures, clinical measures, and multimodal neuroimaging (task-based fMRI, resting state fMRI and diffusion tensor imaging) to examine functioning of brain networks involved in cognitive and mood disturbances.  Dr. Gunning’s program of research focuses primarily on leveraging such techniques to measure how current treatments for depression engage specific network targets as well as informing the development of neuroscience-inspired, scalable interventions. She is Vice Chair of Research in the Weill Cornell Medicine Department of psychiatry. In addition, she is the PI of an RCT that uses a digital therapeutic approach to improve cognitive and functional outcomes in individuals with a previous diagnosis of COVID-19 infection.


Learning Objectives:

1.     To assess the current state of the field regarding the prevalence and pattern of cognitive deficits following Covid-19 infection.

2.     To describe the frequency and pattern of mood disturbances following Covid-19 infection.

3.     To list potential mechanisms of neuropsychiatric symptoms following Covid-19 infection.

4.     To assess some potential scalable treatment approaches.



Members: $20, which includes attendance & 1 CE credit*

Student Members: FREE

Non-members: $40, which includes attendance & 1 CE credit*

*New York Neuropsychology Group is recognized by the New York State Education Department's State Board for Psychology as an approved provider of continuing education for licensed psychologists #PSY-0107 

*New York Neuropsychology Group is approved by the American Psychological Association to sponsor continuing education for psychologists. NYNG maintains responsibility for this program and its content. 

 *Refund Policy: Full refund will be provided if cancellation occurs up to 24 hours prior to the event. Cancellation requests made within 24 hours are non-refundable. 


Castro VM, Gunning FM, McCoy TH, Perlis RH. Mood Disorders and Outcomes of COVID-19 Hospitalizations. Am J Psychiatry. 2021 Apr 6:appiajp202020060842. doi: 10.1176/appi.ajp.2020.20060842.

Douaud, G., Lee, S., Alfaro-Almagro, F. et al. SARS-CoV-2 is associated with changes in brain structure in UK Biobank. Nature (2022).

Gunning FM, Anguera JA, Victoria LW, Areán PA. A digital intervention targeting cognitive control network dysfunction in middle age and older adults with major depression. Transl Psychiatry. 2021 May 4;11(1):269.

Hampshire et al., EClinical Medicine. Cognitive deficits in people who have recovered from Covid-19. 2021 September.

Jaywant A, Vanderlind WM, Alexopoulos GS, Fridman CB, Perlis RH, Gunning FM. Frequency and profile of objective cognitive deficits in hospitalized patients recovering from COVID-19. Neuropsychopharmacology. 2021 Feb 15:1–6. doi: 10.1038/s41386-021-00978-8.    

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